HIV fusion and entry are two steps in the viral lifecycle that can be targeted by several classes of antiviral drugs. The discovery of chemokines focused the attention on cellular co-receptors used by ...
A new study overthrows a long-held theory on how HIV finds its way into host cells. Rather than fusing directly with the host cell membrane, the virus is first engulfed by it to form a vesicle that ...
At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...
The recent report in Nature Medicine that simultaneous inhibition of HIV-1 reverse transcriptase and protease does not prevent resistance to HIV-1 and will not be sufficient for its eradication 1 ...
Scientists may need to rethink the design of drugs meant to block HIV from infecting human cells, according to a new study. That's because the new report shows that HIV doesn't enter cells in the way ...
Circumcision seems to arm men with a degree of protection against HIV, the AIDS virus, but the mechanism underlying this defense has been unclear. A new study bolsters earlier reports implicating the ...
A few decades ago, the idea of an HIV cure sounded unrealistic. Today, doctors describe a carefully documented case where the ...
Boy, 13, wants apology for school seeing him as "reckless teenager." Dec. 2, 2011 — -- A 13-year-old boy who applied to a Hershey, Pa., boarding school told ABC News that it never crossed his ...
Craigslist's entry into a market results in a 15.9 percent increase in reported HIV cases, according to research. When mapped at the national level, more than 6,000 HIV cases annually and treatment ...
President Obama has kept his promise to lift the HIV-positive ban on admission to the United States. The rules lifting the ban are set to take effect Jan 1. That’s 60 days after the new regulation was ...
BEIJING - The Chinese government announced Tuesday the lifting of the 20-year-old ban on entry for foreigners with HIV/AIDS, sexually transmitted diseases and leprosy. According to a statement ...
Future HIV Therapy. 2008;2(5):479-507. PRO 2000 (Figure 2A), a naphthalene sulfonate polymer, binds nonspecifically to the CD4 receptor, but owing to their mechanism of action and their polymer ...