Predictions, picks and odds for NFL Week 16 game
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NFL Week 16 power rankings 2025
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The NFL is all about parity, and Week 16 will offer some high-powered matchups that'll continue to create separation in several key divisions around the league. Last week, the Denver Broncos (12-2) and Los Angeles Rams (11-3) became the first two teams to clinch a playoff spot this season.
If those two results go the Broncos' way and the New England Patriots (11-3) and Buffalo Bills (10-4) also both lose, Denver could also clinch the No. 1 seed in the AFC, securing homefield advantage throughout the playoffs.
NFL RedZone — an around-the-horn live highlight show demonstrating all the action on NFL Sunday — is back for Week 15 of the 2025 season.
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11hon MSN
Prisco's Week 16 NFL picks: Seahawks top Rams on 'TNF,' Packers edge Bears, Jaguars upset Broncos
There's nothing like a good hot streak in December when it comes to picking NFL games Thursday, 8:15 p.m. ET on Amazon Prime This game will go a long way in deciding the NFC West. The Rams beat the Seahawks earlier this year,
With just three games left in the 2025 NFL Season, the NFC East is all but decided. The Philadelphia Eagles (9-5) have opened up a 2.5 game lead over the Dallas Cowboys (6-7-1). Meanwhile, the Washington Commanders (4-10) broke an eight-game losing streak and pushed the Giants (2-12) into their own eight-game losing streak.