Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

So when you touch a hot stove, the nerve endings in your fingers react instantly. But the ouch comes a split-second later, when that information finally reaches your brain. Well, now, scientists have ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...

Gut problems like irritable bowel syndrome are often worse in women. A mouse study reveals a pain pathway involving estrogen, ...

A single nerve injury can quietly reshape the immune system across the entire body. Preclinical research from McGill ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Subscribe to our newsletter for the ...

Stress is often seen as a mental and emotional burden, but its effects reach far deeper than most realize. For many, chronic stress doesn’t just weigh on the mind — it can amplify physical pain in ...

Researchers discovered that nerve injuries can alter the immune system throughout the body, and males and females react very ...

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side ...